MOLECULAR PSYCHIATRY文献大全第9页

Support for a possible schizophrenia vulnerability locus in region 5q22-31 in Irish families.
abstract：:In our genome scan for schizophrenia genes in 265 Irish pedigrees, marker D5S818 in 5q22 produced the second best result of the first 223 markers tested (P = 0.002). We then tested an additional 13 markers and the evidence suggests the presence of a vulnerability locus for schizophrenia in region 5q22-31. This region ...

journal_title：Molecular psychiatry

pub_type： 杂志文章

doi：10.1038/sj.mp.4000258

authors： Straub RE,MacLean CJ,O'Neill FA,Walsh D,Kendler KS

更新日期：1997-03-01 00:00:00
Novel modalities for appraising individual and coordinate pulsatile hormone secretion: the paradigm of luteinizing hormone and testosterone release in the aging male.
abstract：:To quantify aging- and disease-associated alterations in the integrative and interactive components of a pulsatile neuroendocrine axis, novel biomathematical strategies are required. Here, I illustrate as an investigative paradigm otherwise subtle aging-dependent disturbances of the gonadotropin-releasing-hormone (GnR...

journal_title：Molecular psychiatry

pub_type： 杂志文章,评审

doi：10.1038/sj.mp.4000232

authors： Veldhuis JD

更新日期：1997-01-01 00:00:00
Dysthymia in neurological disorders.
abstract：:Dysthymia is characterized by long-lasting periods of lowered mood. Epidemiological studies in the USA and Europe have demonstrated that the prevalence of dysthymia is at least 3% of the general population. Its pervasive occurrence makes dysthymia a public health problem worldwide. One feature of this disorder is its ...

journal_title：Molecular psychiatry

pub_type： 杂志文章,评审

doi：

authors： Akiskal HS,Bolis CL,Cazzullo C,Costa e Silva JA,Gentil V,Lecrubier Y,Licinio J,Linden M,Lopez-Ibor JJ,Ndiaye IP,Pani L,Prilipko L,Robertson MM,Robinson RG,Starkstein SE,Thomas P,Wang Y,Wong ML

更新日期：1996-12-01 00:00:00
Mad cows meet mad yeast: the prion hypothesis.
abstract：:Obscure work on the inheritance of two peculiar genetic traits in yeast has recently collided with work on infectious, neurodegenerative diseases in mammals. The impact illuminates both fields. The yeast work reveals a new mechanism of genetic variation that is based on differences in protein conformation rather than ...

journal_title：Molecular psychiatry

pub_type： 杂志文章,评审

doi：

authors： Lindquist S

更新日期：1996-11-01 00:00:00
Neurobiology of corticotropin releasing factor (CRF) receptors and CRF-binding protein: implications for the treatment of CNS disorders.
abstract：:The actions of CRF in the brain and in the periphery are mediated through multiple binding sites. There are three receptors, CRF1, CRF2 alpha and CRF2 beta, which encode 411, 415 and 431 amino acid proteins and transduce signals via the stimulation of intracellular cAMP production. The recent identification of high-af...

journal_title：Molecular psychiatry

pub_type： 杂志文章,评审

doi：

authors： Behan DP,Grigoriadis DE,Lovenberg T,Chalmers D,Heinrichs S,Liaw C,De Souza EB

更新日期：1996-09-01 00:00:00
Transgenic modeling of neuropsychiatric disorders.
abstract：:Converging advances in the fields of molecular biology, molecular genetics, cellular biology and embryology have given researchers the tools for the targeted delivery and stable germline transmission of foreign genes (transgenes) in the mouse. In the realm of neuropsychiatry, this so-named transgenic technology has be...

journal_title：Molecular psychiatry

pub_type： 杂志文章,评审

doi：

authors： Campbell IL,Gold LH

更新日期：1996-05-01 00:00:00

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